Vampires are one of the three main supernatural races in the Classic World of Darkness and the principle characters of Vampire: The Masquerade and Kindred of the East. They are split into two main types: the Kindred (also called Cainites) and the Kuei-jin.
In the modern nights the majority of mortals have been convinced by The Masquerade that vampires are myths, and thus possess only the knowledge found in the average novel or movie. There are a handful of cults and organizations that are aware of the existence of vampires, such as the Society of Leopold, though their information is often skewed and incomplete.
Most Garou regard vampires as servants of the Wyrm and attack them on sight. Thus, discussion between the two races is incredibly rare and neither side really understands the other, aside from recognition of the mutual antagonism. As most vampires prefer civilization over the wild (largely because werewolves are not believed to spend as much time in cities), encounters between the two are infrequent but usually violent.
Very few of the Awakened realize that vampires are real, though their interaction with both the wondrous and monstrous makes them fairly open-minded to the idea of their existence. Regardless, most mages have no more knowledge concerning vampires than the average mortal gets from modern fiction. Those that have encountered vampires, however, often are intrigued by their apparent abilities to avoid paradox and the levels of quintessence contained in their blood.
Most wraiths couldn't care less about vampires; after all, their posturing and manipulation have no effect on the dead side of the Shroud. A scant few vampires with Auspex have become aware the presence of wraiths, but most of the time, vampires and wraiths leave each other alone.
The exception comes with the nigrimancer Giovanni, who seek to control wraiths, the Shroud, and the Shadowlands. Fear towards these invaders is not unknown among the dead, but far more react towards the Giovanni with rage and fury, especially if the Giovanni attempts to manipulate wraiths against their will. A few wraiths have been known to form alliances with the more "pleasant" Giovanni, but these are rare, and most go out of their way to avoid the Necromancers. Some wraiths have also made contact with the Tremere and the Samedi; these have usually been of a slightly more pleasant nature.