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Typhon is a term derived from Greek mythology that can refer to:
- Typhon, a totem in Werewolf: The Apocalypse;
- Typhon, an Aeon in Mage: The Awakening;
- Typhon, an enigmatic vampire in Vampire: The Masquerade who may be the same being as Set;
- Typhonian Beast, an animal ghoul created by Set, in Vampire: The Masquerade;
- The Path of Typhon or its adherents, Typhonists, in Vampire: The Masquerade;
- Set, who is also sometimes known by the Greek name Typhon.