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In Werewolf: the Apocalypse continuity, the explosion occurred because the Zmei Trevero broke free from the Rite of Draconic Binding, and the resulting battle with Uktena, Silver Fangs, and a Dreamspeaker mage resulted in the explosion. 
A completely alternate explanation for this event comes from Mage: the Ascension canon: the explosion was caused by Void Engineers crew trying to investigate curious alien ship, dubbed ‘The Vivo’ by them, and accidentally causing it to generate miniature black hole.