Sycorax is described as a witch, implying aptitude in the koldunic arts of her Clan. After Demdemeh sunk into Torpor, Sycorax hoped to rule her domain without his interference. She chose the Nok culture as her people, but her rule was immediatly challenged by the Yoruba and their ajogun magicians, who saw Sycorax and the "followers of Cagn" as abominations. Harassed and driven through Africa, she was eventually forced to awaken her sire to come to her aid. by the time, the slave trade had greatly harmed the Yoruba people, which only fanned the hatred of the ajogun.
Despite treaties with foreign Kindred, Sycorax and Demdemeh could not turn the tide in her Clan's favour. Sycorax was eventually slain by some of the remaining ajogun, leaving the african Tzimisce to spread along regional coastlines or outskirts.