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Sebek (also transliterated as Sobek or Sobk) can refer to:
- Sebek, the Pandoran Mockery of the Osiris Lineage in Promethean: The Created
- Sobek, a god of the Pesedjet pantheon in Scion
- Sobk, the deity venerated by the Hem-Ka Sobk in Mage: The Ascension; he may be related to (or an epithet for) the Wyrm
- Sobek, an abomination worshiped by the Abd'al-Sobek in Vampire: The Masquerade
- Sobek, a sixth-Generation Setite who acted as the high priest of the Fire Court during the Giovanni Chronicles in Vampire: The Masquerade