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Mystery can refer to:
- Mystery, a circle of initiation within the Ordo Dracul in Vampire: The Requiem
- Mysteries, a holiday among the Lancea et Sanctum in Vampire: The Requiem
- Mysteries, central goals of the Awakened in Mage: The Awakening
- Mysteries, hunters' term for witches' Dread Powers in Hunter: The Vigil
- Mystery, a Purview in Scion
- The Seven Circles of Mystery of the Tremere in Vampire: The Masquerade