Personable, overzealous and upbeat, Knox is introduced to the player early in-game, via bumping into him in front of the Santa Monica clinic or inside The Asylum. He immediately identify the player character as a Kindred, and explains what a ghoul is.
Not much is known about Knox's past, other than the encounter that led to him becoming Tung's ghoul, and that his previous occupation was being a bounty hunter, employed by Arthur Kilpatrick. He somewhat affectionately refers to Tung as the "nasty dude". Knox is extremely happy with his new status as ghoul, taking the time to explain all the benefits he has gained if asked by the player. By speaking with Knox, the player can obtain valuable information about ghouls in general, as well as a quest that helps to eventually direct you to Tung, allowing you to advance further in the main quest line.
He is described by Tung as being "able to track like a bloodhound". Coming across as initially motor-mouthed and unsuspecting, it is insinuated that he is much cleverer than let on, going so far as to trick the player if their Inspection is not high enough.
Knox is identifiable by his enthusiastic manner of speaking. He will often punctuate dialogue with exclamations such as "aw, man!" or "hey girl/pal, what's up?".
- The Asian vampire
Knox complains of an Asian vampire dude pokin' around Santa Monica. Harrington calls this night specter a scary-ass-Asian-dude-that-can-probably-kick-my-ass. Knox informers the player of his spying on this life-eater and later says "this thing...got wise to me. Now instead of me watchin' him, he's watchin' me, you know." The "Asian vampire" toys with Knox by watching him from a distance, reappearing next to him and then disappearing entirely. The Golden ghouls Asian vampire turns out to be a Cathayan. He can be found in the warehouse of Foxy Boxes. It is highly speculated the Cathayan life-eater murdered Virgil Crumb. Incriminating evidence such Virgil Crumbs' license being found in his previous place employement.
When talking to Bertram Tung, it can be revealed that most of what Knox said to the player during their first meeting were actually pre-made lines Tung had fed him. This also proves that Knox is far sharper than he appears.
It's also worth mentioning that, if the player character is a Malkavian, he refers to Knox as the "golden ghoul".