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The First Change is the name for the first shapeshifting of a young Garou (and for most Fera). Usually it comes along with the first frenzy and the first usage of the Crinos battle-form in highly stressful situations. At some times however, the change can be more placid and straightforward, as the shapeshifter melds into another form.
The First Change for most shapeshifters comes after adolescence for human born shifters, between 2 and 3 years for most animals and around 8 years for Metis.