From the White Wolf Wiki, the most complete White Wolf reference

One of the three heads of the Wyrm, Eater-of-Souls nearly managed to bring on the Apocalypse early. It manifested in the real world at the New World colony of Roanoke. Only the sacrifice of the entire Croatan tribe of Garou managed to banish Eater-of-Souls back to Malfeus.

The sacrifice of the Croatan was so thorough that no new cubs were born to their kinfolk. Their tribal totem was thrown into Slumber and many of their fetishes became inert. Their ancestor spirits also vanished. Eater-of-Souls consumed the entire tribe, both physically and spiritually.

Despite such a monumental sacrifice, Eater-of-Souls was not defeated. It was merely banished from the physical realm.