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Donatello was born into the original family branch in Italy and soon spoiled with wealth. He studied medicine and after he was Embraced, ventured to New York to make profit from the bitter conflicts between the Camarilla and the Sabbat. Establishing himself as a patron over Little Italy, he ensured that his domain was respected by both sects. He was also responsible for the negotiations that ensured the successful raid on New York by the Camarilla. Today, he ensures that the Giovanni profit from the ongoing conflict, and nearly every gang has a share for him reserved.