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The Black Hand can refer to several terms in Vampire: The Masquerade:
- The Black Hand, a sub-sect that operates within the Sabbat
- A general (and essentially incorrect) term for the Sabbat as a whole
- The Tal'mahe'Ra, or "True Black Hand", a sect that once influenced the Sabbat's "False" Black Hand
- The Manus Nigrum, a splinter group from the Tal'mahe'Ra as seen in the Dark Ages
- Black Hand, an expansion for the card game Vampire: The Eternal Struggle that focuses on the Sabbat, specifically the Black Hand
- "Black Hand" notes, which were historically used by the Mafia, seen in the Classic World of Darkness in World of Darkness: Mafia
- Dirty Secrets of the Black Hand, the sourcebook on the "True Black Hand"
- Caine's Chosen: The Black Hand, the sourcebook on the Sabbat's Black Hand