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Antonius can refer to:
- Antonius the Gaul, or Antiorix, the Ventrue member of the Trinity of Constantinople in Vampire: The Dark Ages
- Antonius, or Antinous, the Ventrue Prince of Cairo in Vampire: The Dark Ages who was succeeded by Mukhtar Bey in Vampire: The Masquerade
- Antonius, a member of the Mithraic Singers in Mage: The Ascension