| This Year In|
- 249-251: Reign of Decius and his son Herennius Etruscus.
- 250-251: Decian Persecution. Decius orders the systematic persecution of Christians.
- 251-253: Reign of Trebonianus Gallus with his son Volusian.
- 251-266: Plague of Cyprian. Disease spreads once again through the Roman Empire.
- Decius and his son die in battle against Goths at the Battle of Abrittus, becoming the first Emperors to die in battle against a foreign enemy. Hostilian, the younger son of Decius, becomes Emperor but dies of the plague in weeks.